院長 : 梅田 修二

経歴              .

 
1962/04 生まれ
1988  大分医科大学卒業
1988  熊本大学医学部整形外科入局
1992  熊本大学医学部大学院入学
1996  熊本大学医学部大学院卒業
1997-1999 アメリカ、メーン州ジャクソン研究所留学
1999-2002 熊本機能病院勤務
2002/07    おぐに整形外科開設
   現在に至る
 

.資格             .

 
医学博士(熊本大学)
日本整形外科学会 整形外科専門医
日本リウマチ学会 リウマチ認定医
日本リハビリテーション医学会 認定臨床医


.主な業績           .

 
1)
Joliat MJ, Umeda S, Lyons BL, Lynes MA, Shultz LD.
Establishment and characterization of a new osteogenic cell line (MOS-J)
from a spontaneous C57BL/6J mouse osteosarcoma.
In Vivo. 2002 Jul-Aug;16(4):223-8.


2)
Shultz LD, Lang PA, Christianson SW, Gott B, Lyons B, Umeda S,
Leiter E, Hesselton R, Wagar EJ, Leif JH, Kollet O, Lapidot T, Greiner
DL.
NOD/LtSz-Rag1null mice: an immunodeficient and radioresistant model for
engraftment of human hematolymphoid cells, HIV infection, and adoptive
transfer of NOD mouse diabetogenic T cells.
J Immunol. 2000 Mar 1;164(5):2496-507


3)
Umeda S, Beamer WG, Takagi K, Naito M, Hayashi S, Yonemitsu H, Yi T,
Shultz LD.
Deficiency of SHP-1 protein-tyrosine phosphatase activity results in
heightened osteoclast function and decreased bone density.
Am J Pathol. 1999 Jul;155(1):223-33.


4)
Naito M, Umeda S, Takahashi K, Shultz LD.
Macrophage differentiation and granulomatous inflammation in
osteopetrotic mice (op/op) defective in the production of CSF-1.
Mol Reprod Dev. 1997 Jan;46(1):85-91.


5)
Umeda S, Takahashi K, Shultz LD, Naito M, Takagi K.
Effects of macrophage colony-stimulating factor on macrophages and their
related cell populations in the osteopetrosis mouse defective in
production of functional macrophage colony-stimulating factor protein.
Am J Pathol. 1996 Aug;149(2):559-74.


6)
Ikeda T, Nakamura T, Kikuchi T, Umeda S, Senda H, Takagi K.
Pathomechanism of spontaneous regression of the herniated lumbar disc:
histologic and immunohistochemical study.
J Spinal Disord. 1996 Apr;9(2):136-40.


7)
Naito M, Umeda S, Yamamoto T, Moriyama H, Umezu H, Hasegawa G, Usuda H, Shultz LD, Takahashi K.
Development, differentiation, and phenotypic heterogeneity of murine
tissue macrophages.
J Leukoc Biol. 1996 Feb;59(2):133-8. Review.


8)
Umeda S, Takahashi K, Naito M, Shultz LD, Takagi K.
Neonatal changes of osteoclasts in osteopetrosis (op/op) mice defective
in production of functional macrophage colony-stimulating factor (M-CSF)
protein and effects of M-CSF on osteoclast development and
differentiation.
J Submicrosc Cytol Pathol. 1996 Jan;28(1):13-26.


9)
Takahashi K, Naito M, Umeda S, Shultz LD.
The role of macrophage colony-stimulating factor in hepatic
glucan-induced granuloma formation in the osteopetrosis mutant mouse
defective in the production of macrophage colony-stimulating factor.
Am J Pathol. 1994 Jun;144(6):1381-92.


10)
Takahashi K, Umeda S, Shultz LD, Hayashi S, Nishikawa S.
Effects of macrophage colony-stimulating factor (M-CSF) on the
development, differentiation, and maturation of marginal metallophilic
macrophages and marginal zone macrophages in the spleen of osteopetrosis
(op) mutant mice lacking functional M-CSF activity.
J Leukoc Biol. 1994 May;55(5):581-8.


11)
Usuda H, Naito M, Umeda S, Takahashi K, Shultz LD.
Ultrastructure of macrophages and dendritic cells in osteopetrosis (op)
mutant mice lacking macrophage colony-stimulating factor (M-CSF/CSF-1)
activity.
J Submicrosc Cytol Pathol. 1994 Jan;26(1):111-9.


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